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10X Genomics 3 single cell cdna 461 libraries
3 Single Cell Cdna 461 Libraries, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdna+libraries/pm42271351-235-13-24
Average 86 stars, based on 1 article reviews
3 single cell cdna 461 libraries - by Bioz Stars, 2026-09
86/100 stars

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Sequencing:

Article Title: Mapping glioblastoma's isoform diversity using long-read single-cell analysis.
Article Snippet: .. Among these, 19 were male (70.4%; median age: 63 years) and 8 were female (29.6%; median age: 57 years). cDNA libraries were prepared using the 10x Genomics droplet-based platform and subjected to both Illumina short-read and Oxford Nanopore Technologies (ONT) long-read sequencing (Fig. 1a). ..

Article Title: How Single-Cell Transcriptomics of Hydractinia Is Informing the Evolution of Cnidarian Sensory Systems.
Article Snippet: Fixed single cell samples were diluted to 1,000 cells/μL and shipped on dry ice to the National Institute of Health Intramural Sequencing Center (Bethesda, MD), where cells were thawed, spun, resuspended and loaded onto the 10X Genomics platform for encapsulation, with the capture target of 6,000- 9,000 cells per sample. .. Sequencing libraries were prepared according to the standard 10X Genomics V3 chemistry protocol. cDNA libraries were pooled and sequenced as 150bp pairedend reads and single indexed on an Illumina NovaSeq6000 with 63 million projected clusters per sample. .. Raw sequencing data were processed with the CellRanger v7 pipeline (10X Genomics), using default parameters.

Article Title: A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma
Article Snippet: Single cells, reagents, and 10X Genomics gel beads were encapsulated into individual nanoliter-sized Gelbeads in Emulsion (GEMs), and reverse transcription of polyadenylated mRNA was performed in each droplet at 53°C. .. The cDNA libraries were then completed in a single bulk reaction by following the 10X Genomics Chromium GEM-X Single Cell 3’ Reagent Kit v4 user guide, and 50,000 sequencing reads per cell were generated on the Illumina NovaSeq6000 instrument (RRID:SCR_016387). .. Demultiplexing, barcode processing, alignment, and gene counting were performed using the 10X Genomics CellRanger v8 software (RRID:SCR_023221).

Single Cell:

Article Title: Modeling the role of urokinase-type plasminogen activator, uPA, and circulating cancer-associated fibroblasts (cCAFs) in breast cancer cell extravasation.
Article Snippet: Several samples were made and compared for our analysis: 1) MDA-MB231, CAF23, and DT28 single cells grown in 2D with their standard media, 2) CAF23 mono-clusters, MDAMB231 mono-clusters, and DT28 mono-clusters grown in 3D with Mammocult media for 48 h, and 3) CAF23/MDAMBA231 co-clusters and CAF23/DT28 co-clusters grown in 3D with Mammocult media for 48 h. Since not all cells in the clustering assay became part of a cluster, we used Pluriselect filters to remove non-clustered cells, and then used Accutase to disrupt the clusters. .. A single-cell suspension of each sample was labeled with Hashtag Oligos (HTOs) (Supplemental Table 1) in order to pool samples, and cDNA libraries were made with the 10xGenomics platform. ..

Article Title: A CD4 + T cell-fibroblast crosstalk exacerbates autoimmunity in a mouse model of primary Sjögren disease.
Article Snippet: Single-cell T-cell receptor repertoire sequencing Total CD4+ T cells from the cervical lymph nodes (cLN) of Ctrl and pSjD model mice were purified with CD4 (L3T4) MicroBeads (Miltenyii BioThech, Cat# 130-117-043). .. The cDNA libraries were generated using the Chromium Next GEM Single Cell 5' Reagent Kit v2 (Dual Index) (10x Genomics, Cat# PN-1000265). ..

Article Title: A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma
Article Snippet: Single cells, reagents, and 10X Genomics gel beads were encapsulated into individual nanoliter-sized Gelbeads in Emulsion (GEMs), and reverse transcription of polyadenylated mRNA was performed in each droplet at 53°C. .. The cDNA libraries were then completed in a single bulk reaction by following the 10X Genomics Chromium GEM-X Single Cell 3’ Reagent Kit v4 user guide, and 50,000 sequencing reads per cell were generated on the Illumina NovaSeq6000 instrument (RRID:SCR_016387). .. Demultiplexing, barcode processing, alignment, and gene counting were performed using the 10X Genomics CellRanger v8 software (RRID:SCR_023221).

Suspension:

Article Title: Modeling the role of urokinase-type plasminogen activator, uPA, and circulating cancer-associated fibroblasts (cCAFs) in breast cancer cell extravasation.
Article Snippet: Several samples were made and compared for our analysis: 1) MDA-MB231, CAF23, and DT28 single cells grown in 2D with their standard media, 2) CAF23 mono-clusters, MDAMB231 mono-clusters, and DT28 mono-clusters grown in 3D with Mammocult media for 48 h, and 3) CAF23/MDAMBA231 co-clusters and CAF23/DT28 co-clusters grown in 3D with Mammocult media for 48 h. Since not all cells in the clustering assay became part of a cluster, we used Pluriselect filters to remove non-clustered cells, and then used Accutase to disrupt the clusters. .. A single-cell suspension of each sample was labeled with Hashtag Oligos (HTOs) (Supplemental Table 1) in order to pool samples, and cDNA libraries were made with the 10xGenomics platform. ..

Labeling:

Article Title: Modeling the role of urokinase-type plasminogen activator, uPA, and circulating cancer-associated fibroblasts (cCAFs) in breast cancer cell extravasation.
Article Snippet: Several samples were made and compared for our analysis: 1) MDA-MB231, CAF23, and DT28 single cells grown in 2D with their standard media, 2) CAF23 mono-clusters, MDAMB231 mono-clusters, and DT28 mono-clusters grown in 3D with Mammocult media for 48 h, and 3) CAF23/MDAMBA231 co-clusters and CAF23/DT28 co-clusters grown in 3D with Mammocult media for 48 h. Since not all cells in the clustering assay became part of a cluster, we used Pluriselect filters to remove non-clustered cells, and then used Accutase to disrupt the clusters. .. A single-cell suspension of each sample was labeled with Hashtag Oligos (HTOs) (Supplemental Table 1) in order to pool samples, and cDNA libraries were made with the 10xGenomics platform. ..

Generated:

Article Title: A CD4 + T cell-fibroblast crosstalk exacerbates autoimmunity in a mouse model of primary Sjögren disease.
Article Snippet: Single-cell T-cell receptor repertoire sequencing Total CD4+ T cells from the cervical lymph nodes (cLN) of Ctrl and pSjD model mice were purified with CD4 (L3T4) MicroBeads (Miltenyii BioThech, Cat# 130-117-043). .. The cDNA libraries were generated using the Chromium Next GEM Single Cell 5' Reagent Kit v2 (Dual Index) (10x Genomics, Cat# PN-1000265). ..

Article Title: A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma
Article Snippet: Single cells, reagents, and 10X Genomics gel beads were encapsulated into individual nanoliter-sized Gelbeads in Emulsion (GEMs), and reverse transcription of polyadenylated mRNA was performed in each droplet at 53°C. .. The cDNA libraries were then completed in a single bulk reaction by following the 10X Genomics Chromium GEM-X Single Cell 3’ Reagent Kit v4 user guide, and 50,000 sequencing reads per cell were generated on the Illumina NovaSeq6000 instrument (RRID:SCR_016387). .. Demultiplexing, barcode processing, alignment, and gene counting were performed using the 10X Genomics CellRanger v8 software (RRID:SCR_023221).

Mouse Assay:

Article Title: ACNP 64 th Annual Meeting: Panels, Mini-Panels and Study Groups.
Article Snippet: .. Methods: snRNA-Seq: Mice (60) self-administered OXY (12 days) prior to introducing air-puff paired to drug intake; following classification as punishment sensitive (PS) or resistant (PR), the VP was collected and cDNA libraries from individuals were sequenced (10X Genomics 3’ V3.1). ..

other:

Article Title: Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas.
Article Snippet: For cohort A, the Qiagen blood protocol (Qiagen, #69504) was used with minor adjustments to account for 100mL initial input volume.

Article Title: Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment.
Article Snippet: Libraries were sequenced on an Illumina NovaSeq 6000 S2.



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